Pharmacokinetics and Pharmacodynamics
Pharmacokinetics is ''how body effects drug" & Pharmacodynamics is "how drug effects body"
Pharmacokinetics is currently defined as the study of the time course of drug absorption, distribution, metabolism, and excretion. Clinical pharmacokinetics
is the application of pharmacokinetic principles to the safe and
effective therapeutic management of drugs in an individual patient.
Primary goals of clinical pharmacokinetics include enhancing efficacy
and decreasing toxicity of a patient’s drug therapy. The development of
strong correlations between drug concentrations and their pharmacologic
responses has enabled clinicians to apply pharmacokinetic principles to
actual patient situations.
Pharmacodynamics
refers to the relationship between drug concentration at the site of
action and the resulting effect, including the time course and intensity
of therapeutic and adverse effects.
The effect of a drug present at the site of achievement is determined
by that drug’s binding with a receptor. Receptors may be present on
neurons in the central nervous system
(i.e., opiate receptors) to depress pain sensation, on cardiac muscle
to affect the intensity of contraction, or even within bacteria to
disrupt maintenance of the bacterial cell wall
- Effects of Pharmacokinetics and Pharmacodynamics
- Receptor Binding and Effect
- Toxicodynamics
- Pharmacokinetic Analysis
- Pharmacodynamic Analysis
For more details: https://drugformulation.pharmaceuticalconferences.com/
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